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BugZero found this defect 1210 days ago.
While upgrading or uninstalling Veeam Backup & Replication, the installer stops and displays either of the following messages:
The settings in the registry for one or both of the following services are targeting a drive location that no longer exists: Veeam Guest Catalog Service (VeeamCatalogSvc) Veeam vPower NFS Service (VeeamNFSSvc) The invalid registry entries often occur because during the initial installation of Veeam Backup & Replication a drive with a larger amount of free space than the C:\ drive was present. This is because the installer will detect which drive has the greatest free space and uses that for the above services. If that driver is later removed, the settings in the registry will still point to that drive. During the future upgrade process, when the upgrade installer attempts to check the existing configuration, it finds that it cannot access that drive location.
Check the following registry locations and values. Make sure the path in the registry targets a location that is available. Key: HKEY_LOCAL_MACHINE\SOFTWARE\WOW6432Node\Veeam\Veeam NFSValue Name: RootFolderDefault Path: C:\ProgramData\Veeam\Backup\IRCache\ Key: HKEY_LOCAL_MACHINE\SOFTWARE\Veeam\Veeam Backup CatalogValue Name: CatalogPathDefault Path: C:\VBRCatalog The above "Default" paths shown are what would have been selected if there was no other drive on the Veeam server during the initial install.
How to move the VBRCatalog: https://www.veeam.com/kb1453 The IRCache location is controlled within Veeam Backup & Replication by the mount server setting within a repository using the Veeam server as the Mount server.